Nanoparticle device disrupts cancer genes

MIT researchers have developed a gold nanoparticle device embedded in a hydrogel that can be injected or implanted at a tumor site to disrupt cancer genes.

The nanodevice blocks the gene that confers drug resistance, then launches a new chemotherapy attack against the vulnerable tumor.

Nuria Oliva, Natalie Artzi, and Joao Conde tested the device in mice implanted with a  triple negative breast tumor.  It blocked the gene for multidrug resistant protein 1 and then delivered the chemotherapy drug 5-fluorouracil.  The tumors shrunk by 90 percent in two weeks.

Wearable Tech + Digital Health NYC 2015 – June 30 @ New York Academy of Sciences


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