The National Science Foundation is supporting Third Eye Diagnostics of Philadelphia as it develops a non-invasive, handheld intracranial pressure monitor to rapidly diagnose brain injury.
Cerepress simultaneously records images of the CRV and measures intraocular pressure while pressure in the eye is increased. A medical technician aligns the system by centering the field of view to patient’s pupil. The system then contacts the patient’s cornea and simultaneously collects images of the cornea and the retinal fundus. The contact force increases the IOP and momentarily compresses the CRV. When CRV compression is complete, the Cerepress records the eye pressure, which is equivalent to CRV pressure. CRV pressure is a known to be a good correlate to ICP. Data shows that the combination of CRVP and the pulsatility index produces a correlation with better accuracy than using CRV pressure alone. To determine the pulsatility index, a medical technician uses an optimized Doppler ultrasound probe to obtain blood velocities in the ophthalmic artery.
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